Expression of Bone Morphogenetic Protein 7 in Murine Epididymis Is Developmentally Regulated
نویسندگان
چکیده
منابع مشابه
Bone morphogenetic protein-7 expression in human pyelonephritis.
Bone morphogenetic protein 7 (BMP- 7) is a member of the transforming growth factor (TGF) beta superfamily and is involved in regeneration, repair, and development of specific tissues, for example kidney and skeleton. The experimental studies have shown its protective role against fibrotic processes. Tubulointerstitial changes are present in the pyelonephritic kidney which progresses to fibrosi...
متن کاملperiplasmic expression of a novel human bone morphogenetic protein-7 mutant in escherichia coli
background: bone morphogenetic proteins (bmps) belong to the transforming growth factor-β (tgf-β) superfamily, and play an important role in bone metabolism. recombinant forms of bmp-2 and bmp-7 are the only bmps used clinically. in this study the mature part of human bone morphogenetic protein-7 (bmp-7) was engineered through substitution of the bmp-7 n-terminal sequence by heparin-binding sit...
متن کاملa comparison of bone morphogenetic protein-7 mutant expression in prokaryotic and eukaryotic hosts
objective: bone morphogenetic protein-7 (bmp-7) is a multifunctional growth factor predominantly recognized for its osteoinductive properties. due to the high cost of this protein, the availability of bmp-7 for treatment is limited. the heterologous production of recombinant hbmp-7 has been performed in a number of expression systems. in this study a novel form of bmp-7 was expressed in eukaryo...
متن کاملchanges in the expression of bone morphogenetic protein 7 and tamm– horsfall protein in the early stages of diabetic nephropathy
background bone morphogenetic protein 7 (bmp7) has been suggested to play a protective role against kidney injury in chronic kidney disease. objectives to identify the critical molecular regulators in the early stage of diabetic nephropathy, we studied the expression of bmp7 and 2 important kidney-specific markers, podocin and tamm–horsfall protein (thp). materials and methods a diabetic nephro...
متن کاملCAP1 expression is developmentally regulated in Xenopus
We have cloned and characterized a Xenopus member of the cyclase associated protein (CAP) gene family. xCAP1 is expressed as a maternal transcript, but is up-regulated prior to gastrulation and subsequently localizes to head mesenchyme, lens, otic vesicle, and trunk mesoderm including the pronephros. At different stages, the gene also appears to differentiate surface from deep (sensorial) ectod...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1999
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod60.6.1503